General Osteopathic Treatment and the Neuro-Endocrine-Immune Axis
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Exploration of GOT, Heart Rate Variability, and Vagal Stimulation
Instructor: Pascal Grolaux, DO(UK)
Lesson content
- You will review the General Osteopathic Treatment (GOT) as pictured by JM Littlejohn and promoted by J Wernham.
- You will understand the central autonomic network and its relation to the body systems (e.g., the brain-heart-axis).
- You will learn the basics of the neuro-endocrine-immune system's bi-directional communication with the autonomic nervous system (ANS) in cases relating to autoimmune diseases, chronic pain syndrome, mental health, and more.
- You will discover the osteopathic centres in relation to the neuro-endocrine-immune system and will integrate them along the practice of the GOT.
- You will understand how to perform osteopathic manipulative treatment along the practice of the GOT, specifically targeting the ANS and the immune system.
- You will understand how the GOT via relevant and appropriate general and specific techniques acts on these systems and will impact the sympathetic-vagal balance as demonstrated by heart rate variability analysis.
Summary of the themes that will be seen:
- Review of the General Osteopathic Treatment and the osteopathic centres
- Neuroanatomy: ANS review; and specifically, the vagus nerve
- The limbic system and the central autonomic network
- Neuro-endocrine-immunology (NEI) and the anti-inflammatory reflexes
- The heart-brain axis
- Short-term heart rate variability analysis and the sympathetic-vagal balance
- Applied osteopathic treatment targeting the neuro-endocrine-immune system and the vagus nerve to modulate the sympathetic-vagal balance
Day 1:
Theory:
- Review of the philosophy and principles of the GOT
- Review of the neuroanatomy and the neurophysiology of the
ANS and specifically, the vagus nerve. - The neuroanatomy and functions of the autonomic central
network, and the limbic system. - The anti-inflammatory reflexes in relation to the vagus nerve.
Day 2:
Theory:
- The heart-brain axis.
- Overview of the osteopathic centres linked with the ANS and
the neuro-endocrine-immune centers. - Heart rate variability analysis based on short-term EKG
Practice:
- Applied osteopathic treatment, general and specific treatment,
targeting the ANS and neuro-endocrine-immune reflexes (groups
of two). - Practice of heart rate variability analysis – Biomarkers analysis
and discussion
Days 3 and 4:
Practice:
- Practice of heart rate variability analysis (groups of two).
Baseline analysis. Discussion. - Applied osteopathic treatment, general and specific treatment,
targeting the ANS and neuro-endocrine-immune reflexes (group
of two). - Practice of heart rate variability analysis (group- of two). Post
treatment assessment.
Discussion & Review of the Course
Dates:
- 2026-04-23
- 2026-04-24
- 2026-04-25
- 2026-04-26
Cost: $1300 CAD
